The present investigations were aimed to formulate the topical herbal analgesic and anti-inflammatory gel. Gels were formulated using different concentration of carbomer-940 and Na CMC as gelling agent and Boswellia serrata extract in 10% concentration. Before the formulation, the quality of raw material was standardized by their analysis including the development of HPTLC fingerprint. All the formulations developed have pH within the range of skin pH non-staining and having good spredability. The gels were evaluated their physical properties, pharmacological potency, safety, efficacy in-vivo and in-vitro studies. The stability studies were done in accordance with ICH guidelines. Since no significant changes were observed after three months. So it concluded that the formulation were stable.
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